Announcement

Collapse
No announcement yet.

Half ex steroids users are hypogonadal

Collapse
X
Collapse
  •  

  • Half ex steroids users are hypogonadal

    Steroids users will have caused lasting damage to their hormone balance after a couple of years, we wrote recently. That post was based on a Danish study that was recently published in PLoS One. A year before, researchers at Harvard Medical School published a similar study. While it's not as solid as the Danish study, the results are just as unpleasant. According to the Harvardians, half of all ex steroids users never recover their hormone balance.



    Study

    The researchers studied 55 male recreational bodybuilders. They only took people who could do at least 1 rep with 125 kg on the bench press.



    Of the group, 19 bodybuilders had used steroids in the past but had since stopped. Ex-users who had had testosterone therapy because their testes no longer produced enough male sex hormone were excluded from the study. The 36 bodybuilders who said they had never used steroids were subjected to various tests to check whether they really were natural bodybuilders.



    Results
    The percentage of ex-users with a relatively high testosterone level was noticeably higher than among the never-users. And yes, the differences between the groups were statistically significant.










    The ex-users had less free testosterone in their blood than the never-users. The difference between the two groups was not quite statistically significant. The differences in libido and testes size were significant between the two groups.










    Four ex-users had only stopped cycling 4-6 months before the experiment. The rest were already at least 7 months clean. Excluding the data for the four recent ex-users did not change the overall findings.



    The researchers summarise the results of their study in this table.



    Conclusion
    Just over half of the ex-users showed "pronounced symptoms of anabolic steroids withdrawal hypogonadism", according to the Harvardians. And although they only studied a small number of bodybuilders, they believe the results of their study give reason for concern.



    "The present observations, despite their limitations, suggest that anabolic steroids induced hypogonadism likely represents an emerging issue in the growing world population of anabolic steroids users - an issue still apparently underrecognized in the scientific literature", they wrote. "Hypogonadal symptoms are of particular concern because they may induce individuals to quickly resume anabolic steroids use after stopping a prior course of these drugs, in an attempt to self-treat dysphoric sexual and mood symptoms."



    "Repeated cycles of anabolic steroids re-use may then lead to anabolic steroids dependence, a disorder that appears to develop in as many as 30% of illicit steroids users."



    "To prevent anabolic steroids dependence, and to reduce the risk of prolonged hypogonadal syndromes, hypogonadal patients will likely require endocrinological treatment to restore normal hypothalamic-pituitary-testicular function, possible antidepressant treatment (if depressive symptoms are pronounced), and substance-dependence treatment to reduce the risk of relapse into steroids use."



    Source:
    Addiction. 2015 May;110(5):823-83.

      Posting comments is disabled.

    Categories

    Collapse

    Article Tags

    Collapse

    Latest Articles

    Collapse

    • YK11 can be detected in drug testing...
      by AnaboleX
      Test for doping with YK11



      About five years ago YK11 came on the market: a steroid-like substance developed by Japanese scientists with an anabolic effect. YK11 is a SARM, but also a myostatin inhibitor. It became popular as a research chemical and 'rogue supplement'. German doping hunters from the German Sport University Cologne have developed a doping test for this curious substance.


      ...
      01-07-2019, 03:39 PM
    • Tren may alter DNA sequences...
      by AnaboleX
      Toxicol Sci. 2002 Dec;70(2):202-11.
      In vitro and in vivo effects of 17beta-trenbolone: a feedlot effluent contaminant.

      Wilson VS1, Lambright C, Ostby J, Gray LE Jr.
      Author information

      Abstract

      Concern has arisen regarding the presence and persistence of trenbolone in the environment. Trenbolone acetate is an anabolic steroid used to promote growth in beef cattle. It is hydrolyzed to the active compound, 17beta-trenbolone (TB), which is also one of the metabolites...
      01-07-2019, 03:33 PM
    • Plasma steroid-binding proteins: primary gatekeepers of steroid hormone action.
      by WesleyInman



      Abstract

      Biologically active steroids are transported in the blood by albumin, sex hormone-binding globulin (SHBG), and corticosteroid-binding globulin (CBG). These plasma proteins also regulate the non-protein-bound or 'free' fractions of circulating steroid hormones that are considered to be biologically active; as such, they can be viewed as the 'primary gatekeepers of steroid action'. Albumin binds steroids with limited specificity and low affinity, but its high concentration...
      12-26-2018, 01:05 PM
    • CBD and hemp are now legal in the U.S
      by AnaboleX
      CBD and hemp are now legal in the U.S., so what does that mean for pot companies?






      Legalization of hemp leaves CBD decisions up to the states, could boost hemp farming in U.S.



      Bloomberg President Donald Trump signed the farm bill on Thursday, which legalized industrial hemp in the U.S. By
      MaxA. Cherney

      Tech reporter




      Industrial hemp is now legal in the U.S.,...
      12-21-2018, 03:12 PM
    • 7 Richest Bodybuilders In The World
      by AnaboleX
      7 Richest Bodybuilders In The World




      Though most of us have a hard time getting up from the couch and going to the gym, the people on this list have shown maximum commitment to their goals and made it to the top. They’ve had their fair share of sacrifices, but they’ve also enjoyed the wealth and social benefits that come with making it big in the bodybuilding world and beyond. For these A-listers, pumping iron became a full-time job, and it paid
      ...
      12-11-2018, 01:35 PM
    • Transgender Boxer (Female to Male) Patricio Manuel Makes History with First Pro Win
      by AnaboleX
      Transgender Boxer (Female to Male) Patricio Manuel Makes History with First Pro Win


      Los Angeles (AFP) – Transgender boxer Patricio Manuel made history Saturday with a unanimous decision victory over Mexican super-featherweight Hugo Aguilar in Indio, California.

      Manuel, 33, became the first transgender male to fight professionally in the United States.

      “I wouldn’t trade any of it. It was worth everything I went through to get to this point,” Manuel said,
      ...
      12-10-2018, 01:39 PM
    Working...
    X